What is Osteoarthritis?

A healthy knee contains synovial fluid, a viscous liquid that is responsible for lubricating the joint and absorbing shocks. Synovial fluid also has anabolic anti-inflammatory and analgesic effects. Hyaluronic acid is a major component of normal synovial fluid and contributes to the fluid’s viscoelastic properties. Changes in the synovial fluid and degeneration of joint structures may lead to OA knee pain. Pain from OA of the knee may be worse during weight-bearing activities, particularly when climbing stairs or bending. For some people, pain may be present even at rest.


Early and Moderate Stage Osteoarthritis

CINGAL is designed to provide Fast Acting and Long Lasting Pain Relief in a Single Injection.


Cingal™ is the first and only single-injection treatment that quickly relieves your OA knee pain while providing sustained pain reduction. It is used for patients who do not get adequate pain relief from simple pain relievers like acetaminophen or from exercise and physical therapy.

Cingal™ combines the benefits of a trusted anti-inflammatory with Monovisc® to relieve OA knee pain. The anti-inflammatory component provides fast pain relief generally beginning 24 hours after administration and the hyaluronic acid gives effective OA pain relief for up to 6 months.

Cingal™ was generally well tolerated; no serious adverse events were reported.

How long will the treatment last?

CINGAL provides pain relief as early as Days weeks with faster and longer lasting pain relief up that may last for up to 6 months. Although individual results may vary, some people feel relief quickly after getting the injection. Talk to your healthcare specialist to see if a CINGAL injection is right for you.

What are the side effects?

  • Mild to transient Pain, warmth and slight swelling immediately after injection.
  • Injection Site pain (Short term)
  • If you experience any of this side effects, please contact your doctor immediately.

Cingal product information

For More Information, please click here.